Von Willebrand's disease (VWD) is a common and usually mild, inherited bleeding disorder in people and in dogs. It is caused by a lack of Von Willebrand factor (VWF), which plays an essential role in the blood clotting process.

Normally the body responds to an injury causing bleeding through a complex defense system. This consists of local changes in the damaged blood vessels, activation of blood cells called platelets, and the coagulation process.

A reduction in Von Willebrand factor leads to abnormal platelet function and prolonged bleeding times.

Affected dogs are prone to bleeding episodes such as nose bleeds, and generally experience increased bleeding with trauma or a surgical procedure.

Screening for VWD should be performed on BOTH sire and dam prior to breeding (or before surgery)

• About Von Willebrand's Disease

• Von Willebrand's Disease